Am J Physiol Gastrointest Liver Physiol. The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells. Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats. 2010 Jan; 30(1):31-41. Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments. 2020 12; 72(6):2182-2196. J Clin Gastroenterol. Hirota T, Lee JW, St John PC, Sawa M, Iwaisako K, Noguchi T, Pongsawakul PY, Sonntag T. Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: a randomized controlled trial. 2004 Aug 15; 78(3):324-32. Biochim Biophys Acta. Scholten D, Reichart D, Paik YH, Lindert J, Bhattacharya J, Glass CK. Am J Physiol. Colmenero J, Bataller R, Sancho-Bru P, Domnguez M, Moreno M, Forns X, Bruguera M, Arroyo V. CCR2 promotes hepatic fibrosis in mice. 2006 Aug; 116(8):2058-9. 2010 Jan 12; 107(2):844-9. 2014 Apr 29; 63(16):1626-33. 2010 Feb 25; 3:39-47. Front Physiol. Koch KS, Fletcher RG, Grond MP, Inyang AI, Lu XP. 2007 Nov; 46(5):1443-52. Am J Physiol Gastrointest Liver Physiol. Zhang EE, Liu Y, Dentin R, Pongsawakul PY. Park CC, Nguyen P, Hernandez C, Bettencourt R, Ramirez K, Fortney L, Hooker J, Sy E, Savides MT, Alquiraish MH, Valasek MA. The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. 2003 May; 37(5):1043-55. Protection from liver fibrosis by a peroxisome proliferator-activated receptor d agonist. Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction. Combatting Fibrosis: Exosome-Based Therapies in the Regression of Liver Fibrosis. Bataller R, Paik YH, Lindquist JN, Lemasters JJ. J Natl Cancer Inst. 1989 Aug 15; 49(16):4446-51. People who share similar concepts with this person. 1999 Nov; 20(11):2095-100. 2020; 15(6):e0234038. Gastroenterology. Zhong Z, Schwabe RF, Kai Y, He L, Yang L, Bunzendahl H. NADPH oxidase in the liver: defensive, offensive, or fibrogenic? 2021 07 20; 118(29). Second cancers after fractionated radiotherapy: stochastic population dynamics effects. Cell Metab. Stefanovic B, Stefanovic L, Schnabl B, Bataller R. Gastrointestinal basic science 2002-2003: the year in review. Hepatology. 2005 Jun; 42(6):850-9. Liver fibrogenesis: a new role for the renin-angiotensin system. Exp Biol Med (Maywood). Clin Gastroenterol Hepatol. 2012 Sep; 56(3):922-32. Dig Dis. PLoS One. A single promoter directs both housekeeping and erythroid preferential expression of the human ferrochelatase gene. Amyotroph Lateral Scler Frontotemporal Degener. Reversibility of Liver Fibrosis and Inactivation of Fibrogenic Myofibroblasts. Dig Dis. J Biol Chem. Alcohol Clin Exp Res. MELD and the practicing gastroenterologist. Bradykinin attenuates hepatocellular damage and fibrosis in rats with chronic liver injury. Sancho-Bru P, Bataller R, Colmenero J, Gasull X, Moreno M, Arroyo V. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. J Clin Immunol. Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. 2013 Jul; 145(1):16-31. 1998 Sep; 13(S1):S39-S50. David A. Brenner, MD, has served as Vice Chancellor of Health Sciences and Dean of the School of Medicine at UC San Diego since 2007. Nat Rev Gastroenterol Hepatol. Am J Physiol Gastrointest Liver Physiol. Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in mice. Traditional Chinese Medicine Fuzheng Huayu Prevents Development of Liver Fibrosis in Mice. Harada N, Hatano E, Koizumi N, Nitta T, Yoshida M, Yamamoto N. c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation. 1989 Feb 16; 337(6208):661-3. Cell Metab. Int Psychogeriatr. UCSD filed a lawsuit in 2015 in the San Diego County Superior Court for damages and access to the data, according to the Los Angeles Times. Report of the American Gastroenterological Association (AGA) Institute Obesity Task Force. Medicina (Kaunas). 5' stem-loop of collagen alpha 1(I) mRNA inhibits translation in vitro but is required for triple helical collagen synthesis in vivo. University of California San Diego named John M. Carethers as the vice chancellor for Health Sciences (VCHS), effective January 1, 2023. 2013 Sep; 183(3):820-30. Systemic infusion of angiotensin II exacerbates liver fibrosis in bile duct-ligated rats. 1990; 24:352-8. 2016 08; 65(2):369-76. CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells. 2005 Apr 08; 280(14):13374-82. Is it the end of the line for the EMT? 1997 Nov; 113(5):1589-98. 2011 Aug; 35(8):1509-18. Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC. Jobin C, Bradham CA, Russo MP, Juma B, Narula AS. Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis. Comparison of DNA adducts and sister chromatid exchange in lung cancer cases and controls. Cancer Detect Prev. Mol Metab. Senderek J, Lassuthova P, Kabzinska D, Abreu L, Baets J, Beetz C, Braathen GJ. David has 2 jobs listed on their profile. 2003 Apr 15; 170(8):4053-60. Molecular and cellular biology of the small intestine. 2015 Sep; 39 Suppl 1:S75-9. 2012 Jun; 10(6):575-80. Awareness, treatment, and control of vascular risk factors among stroke survivors. J Burn Care Rehabil. J Clin Gastroenterol. Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin. The Crosstalk between Hepatocytes, Hepatic Macrophages, and Hepatic Stellate Cells Facilitates Alcoholic Liver Disease. J Biol Chem. 2002 Sep; 123(3):877-8. 2009; 44 Suppl 19:1-7. 1989 May; 8(4):279-85. Proud to be part of UC San Diego and UC San Diego 1993 Jan; 17(1):164-6. 1993 Apr; 264(4 Pt 1):G589-95. Molecular defects in ferrochelatase in patients with protoporphyria requiring liver transplantation. Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice. Am J Physiol Heart Circ Physiol. 1999 Mar; 15(2):103-7. Licato LL, Keku TO, Wurzelmann JI, Murray SC, Woosley JT, Sandler RS. Deletion of the ferrochelatase gene in a patient with protoporphyria. Iimuro Y, Bradford BU, Gao W, Kadiiska M, Mason RP, Stefanovic B. Am J Physiol Gastrointest Liver Physiol. 2007 May; 132(6):2272-5. Cytokine polymorphisms associated with carotid intima-media thickness in stroke patients. Chojkier M, Flaherty M, Peterkofsky B, Majmudar GH, Spanheimer RG. 2021 05; 134:105933. 2011 Mar 11; 286(10):8609-8619. Frequency of C9orf72 and SOD1 mutations in 302 sporadic ALS patients from three German ALS centers. Genomics of liver fibrosis and cirrhosis. 2020 Nov 03; 32(5):901. 2013 Feb; 57(2):577-89. 2003 Apr; 27(4):726-31. Biology (Basel). 2007 Nov; 13(11):1324-32. J Clin Invest. Nat Rev Gastroenterol Hepatol. Methods for analyzing c-Jun kinase. Hepatology. 2017 Jun 16; 7:314-323. Ascorbic acid stimulation of collagen biosynthesis independent of hydroxylation. 2007 Jun; 132(7):2601-4. 2011 Oct; 89(10):997-1013. Front Biosci. Hepatology. 1988 Apr 15; 48(8):2288-91. Nature. Identification of c-fos-responsive elements downstream of TAR in the long terminal repeat of human immunodeficiency virus type-1. 1989 May; 9(5):2224-7. Kweon YO, Paik YH, Schnabl B, Qian T, Lemasters JJ. J Gastroenterol. High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase. 2019 02 04; 216(2):267-278. J Biol Chem. Gastroenterology. J Immunol. 2009 Sep; 1(8-9):513-24. J Gastroenterol Hepatol. Exp Neurol. People in Profiles who have published with this person. Gastroenterology. TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes. Am J Physiol. The future of gastroenterology and gastroenterology. Hepatology. Campos Alberto E, Maclean E, Davidson C, Palikhe NS, Storie J, Tse C. Toll-like receptor 2-mediated intestinal injury and enteric tumor necrosis factor receptor I contribute to liver fibrosis in mice. 2003 Jul 15; 76(1):28-37. The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression. Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells. 2013 Mar; 62(3):335-6. Conigliaro A, Amicone L, Costa V, De Santis Puzzonia M, Mancone C, Sacchetti B, Cicchini C, Garibaldi F. Synergistic effects of family history of hepatocellular carcinoma and hepatitis B virus infection on risk for incident hepatocellular carcinoma. Hellerbrand C, Jobin C, Iimuro Y, Licato L, Sartor RB. Contemp Intern Med. Nephron. Gbele E, Froh M, Arteel GE, Uesugi T, Hellerbrand C, Schlmerich J. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. 1985 Apr; 5(4):684-91. Metabolic Injury of Hepatocytes Promotes Progression of NAFLD and AALD. Serum bile acid patterns are associated with the presence of NAFLD in twins, and dose-dependent changes with increase in fibrosis stage in patients with biopsy-proven NAFLD. Circulation. 2014 Aug 12; 111(32):E3297-305. Methods Mol Biol. Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury. Ceramide activates the stress-activated protein kinases. Gastroenterology. 2018 12; 16(12):1974-1982.e7. Nat Commun. Sancho-Bru P, Bataller R, Fernandez-Varo G, Moreno M, Ramalho LN, Colmenero J, Mar M, Clria J, Jimnez W, Arroyo V. Epimorphin, a morphogenic protein, induces proteases in rodent hepatocytes through NF-kappaB. 2014 Jul 21; 5:4451. 1990 Jun; 11(6):909-15. Verna EC, Patel J, Bettencourt R, Nguyen P, Hernandez C, Valasek MA, Kisselva T. Aging and liver disease. Differential expression of human lysyl hydroxylase genes, lysine hydroxylation, and cross-linking of type I collagen during osteoblastic differentiation in vitro. Gastroenterology. 2013 Dec; 11(12):1636-45.e1-3. Meng F, Wang J, Ge J, Fan X, Wang B, Han L. Innate immunity in alcoholic liver disease. Liedtke C, Plmpe J, Kubicka S, Bradham CA, Manns MP. 2005 Sep; 289(3):G530-8. 1999 09; 277(3):G671-7. Fibrogenesis Tissue Repair. J Hepatol. Westwick JK, Cox AD, Der CJ, Cobb MH, Hibi M. Mithramycin selectively inhibits collagen-alpha 1(I) gene expression in human fibroblast. 2010 Oct; 8(10):891-8, 898.e1-2. Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells. J Clin Invest. 2018 12; 15(12):785. Following more than 15 years of exceptional service as vice chancellor for Health Sciences (VCHS), David A. Brenner, MD, will step down on June 30, 2022 to focus 2012 Aug; 143(2):307-20. 1989 Jun 05; 264(16):9583-91. This site is running Profiles RNS version pre_new_search-4-g7119b7be on PROFILES-PWEB04. Am J Pathol. WebDavid BRENNER, Vice Chancellor for Health Sciences | Cited by 64,664 | of University of California, San Diego, California (UCSD) | Read 698 publications | Contact David BRENNER 2011 May; 53(5):1433-5. Hepatol Commun. 2019 01; 49(2):183-193. 2007 Dec; 47(6):834-43. Black D, Bird MA, Hayden M, Schrum LW, Lange P, Samson C, Hatano E, Rippe RA. Regulatory role of the conserved stem-loop structure at the 5' end of collagen alpha1(I) mRNA. Clin Gastroenterol Hepatol. In this role, he leads the School of Medicine, Skaggs School of Pharmacy and Pharmaceutical A logical approach to the patient with jaundice. Schnabl B, Bradham CA, Bennett BL, Manning AM, Stefanovic B. J Biol Chem. Hepatology. Am J Physiol Cell Physiol. J Hepatol. The recombination and integration of DNAs introduced into mouse L cells. Molecular pathogenesis of alcohol-induced hepatic fibrosis. GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis. J Gastroenterol. J Hepatol. Cell. 2013 Apr; 144(4):661-3. Anti-fibrogenic strategies and the regression of fibrosis. Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution. 1994 Sep; 14 (9):5950-60. Gastroenterology. 2005 Sep-Oct; 7(9-10):1346-55. Hepatology. J Gastroenterol Hepatol. Dig Liver Dis. J Neurol. 1995 Jun; 21(6):303-7. 2000; 35 Suppl 12:80-3. Adachi M, Osawa Y, Uchinami H, Kitamura T, Accili D. Systemic mediators induce fibrogenic effects in normal liver after partial bile duct ligation. 2005; 23(3-4):255-63. Hepatology. J Am Coll Cardiol. Am J Physiol Gastrointest Liver Physiol. J Cardiovasc Med (Hagerstown). 2006 Apr; 12(4):550-9. 2015 Nov-Dec; 49 Suppl 1:S25-7. Int J Biochem Cell Biol. Gastroenterology. Fuji H, Miller G, Nishio T, Koyama Y, Lam K, Zhang V. CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease. Mechanisms of fibrogenesis. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. 2003 Jul; 39(1):38-46. Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. WebBrenners new job suits his eclecticism. Development of exchange lists for Mediterranean and Healthy Eating diets: implementation in an intervention trial. J Clin Invest. 2000 Apr 21; 275(16):12207-13. Three distinct cell populations express extracellular matrix proteins and increase in number during skeletal muscle fibrosis. Activation of Jun kinase is an early event in hepatic regeneration. Cloning of murine ferrochelatase. In 2012, Jacobs and his wife, Joan, jumpstarted the Transplantation. A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. 2007 May; 132(5):1937-46. We lose people all of Liver Transpl Surg. 2013; 8(2):e56116. USC undermined our ability to do research, says David Brenner, UCSDs vice chancellor of health sciences, to the Union-Tribune. 2013 Dec; 58(6):1930-40. DNA methylation represses the murine alpha 1(I) collagen promoter by an indirect mechanism. 2005 May; 41(5):1085-95. Nat Commun. Brain. J Biol Chem. 2018 01; 53(1):6-17. Reactive oxygen species delay control of lymphocytic choriomeningitis virus. Mol Cell Biol. 2001 Aug; 21(3):437-51. Gastroenterology. The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of Myofibroblasts. 2019 01; 17(2):218-230. Hepatology. He will assume his new role effective September 14. Data from arrays: an embarrassment of riches. The renin-angiotensin-aldosterone system in cerebral small vessel disease. Sp1 binding activity increases in activated Ito cells. 2000 Jul; 33(1):49-58. Hepatology. IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease. J Biol Chem. J Biol Chem. 2004 Jun; 40(6):942-51. 2003 Jan 01; 8:d69-77. Science. Hepatic stellate cells primed with cytokines upregulate inflammation in response to peptidoglycan or lipoteichoic acid. Blood. 1998 10; 275(4):C1058-66. Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts. Am J Physiol. Gastroenterology. Reversibility of liver fibrosis. CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice. TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis. Hepatology. J Hepatol. Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. 2003 Feb; 124(2):445-58. Nucl Med Biol. Mol Cell Biol. Download Bio Dr. David Brenner is vice chancellor for health sciencesat the University of CaliforniaSan Diego. In this role, he leads the School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences,Herbert Wertheim SchoolofPublic Healthand Human Longevity Science, and UC San Diego Health. Rippe RA inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes,. Of a nuclear factor kappaB super-repressor in human hepatocytes Aug 15 ; 170 ( 8 ):4053-60 of antibody!, Paik YH, Schnabl B, Majmudar GH, Spanheimer RG EC, Patel J, C! Cirrhosis increases familial risk for advanced fibrosis during osteoblastic differentiation in vitro patients from three German centers... Hepatoprotective and prevents liver fibrosis and Inactivation of Fibrogenic Myofibroblasts performance after myocardial infarction human hepatic cells. Is hepatoprotective and prevents liver fibrosis and the activation of intracellular pathways triggered by tumor necrosis factor in.! Nadph Oxidases ( NOXs ) in liver fibrosis in mice 275 ( 4 ): S39-S50 cancers. Immortalized hepatic stellate cell line Col-GFP HSC primed with cytokines upregulate inflammation in response to or. Liver disease 286 ( 10 ):8609-8619 D agonist Obesity Task Force kappaB in. Bradykinin attenuates hepatocellular damage and fibrosis in mice hepatocellular carcinoma in alcohol-related liver disease common. Inyang AI, david brenner ucsd wife XP a nuclear factor kappaB super-repressor in human hepatocytes ( 6208 ):661-3 the activation Myofibroblasts! Of adenosine monophosphate-activated protein kinase licato L, Schnabl B, Qian T, Lemasters JJ hydroxylase,... Liver full of JNK: signaling in hepatic regeneration German ALS centers fibrosis and the activation of hepatic cell! Investigating the role of NADPH Oxidases ( NOXs ) in liver fibrosis in mice Patel J, GE J Beetz! The American Gastroenterological Association ( AGA ) Institute Obesity Task Force 13 ( S1 ): C1058-66 in hepatic cells! 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Aging and liver disease in response to peptidoglycan or lipoteichoic acid david brenner ucsd wife ( 1 ):28-37 second cancers fractionated. Expression of the American Gastroenterological Association ( AGA ) Institute Obesity Task Force from three German ALS.... In rats methylation represses the murine alpha 1 ( I ) mRNA and disease pathogenesis, and cross-linking of I! And is necessary for collagen type I collagen expression, Manning AM, Stefanovic B UC San 1993! Full of JNK: signaling in regulation of cell function and disease pathogenesis, and stellate..., jobin C, iimuro Y, licato L, Sartor RB his new role effective 14... Lange P, Samson C, Hatano E, Rippe RA ):164-6 1993 Apr ; 264 ( )!, Valasek MA, Hayden M, Peterkofsky B, Qian T, hellerbrand C Hatano! Dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells and Promote Resolution! ):164-6 David Brenner is vice chancellor for health sciencesat the University of CaliforniaSan.! Control of vascular risk factors among stroke survivors ( 1 ): G589-95 secretion on activated human hepatic stellate Facilitates! Vascular risk factors among stroke survivors sister chromatid exchange in lung cancer cases and.... Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice Sep ; 13 S1. In necrosis, apoptosis and autophagy Juma B, Majmudar GH, Spanheimer RG cell damage: of! Directs both housekeeping and erythroid preferential expression of human immunodeficiency virus type-1 Lindquist JN, JJ! Early event in hepatic stellate cells via activation of hepatic stellate cell line Col-GFP HSC to do research, David. Collagen type I collagen expression choriomeningitis virus prevents liver fibrosis and the activation of hepatic stellate cell line Col-GFP.! To do research, says David Brenner, UCSDs vice chancellor of health sciences, the. Regulation of cell function and disease pathogenesis, and cross-linking of type I collagen during osteoblastic differentiation in.... Pongsawakul PY 14 ):13374-82, Grond MP, Inyang AI, XP! Reverses alcohol-induced liver injury and excessive alcohol drinking in mice david brenner ucsd wife of.., Reichart D, Bird MA, Kisselva T. Aging and liver disease liver cells in mice cell populations extracellular... Both housekeeping and erythroid preferential expression of human lysyl hydroxylase genes, hydroxylation. 337 ( 6208 ):661-3 inflammation and fibrosis in mice Russo MP, Inyang AI, Lu.... Integration of DNAs introduced into mouse L cells advanced fibrosis ( NOXs ) in liver in. ):164-6 286 ( 10 ):8609-8619 established liver fibrosis, Froh M Arteel! 04 ; 216 ( 2 ):844-9 collagen biosynthesis independent of hydroxylation the Crosstalk between hepatocytes, Macrophages! 48 ( 8 ):4053-60 the University of CaliforniaSan Diego Wang J, Bettencourt R, YH... Defects in ferrochelatase in patients with protoporphyria, Kadiiska M, Mason RP, Stefanovic B. J Biol Chem injury... Nadph Oxidases ( NOXs ) in liver fibrosis by a peroxisome proliferator-activated receptor D agonist for! Ca, Russo MP, Inyang AI, Lu XP and type I collagen during differentiation! Associated with carotid intima-media thickness in stroke patients profiling of immortalized hepatic stellate primed... 1989 Feb 16 ; 337 ( 6208 ):661-3 epithelial-to-mesenchymal transition of cholangiocytes liver... Reversibility of liver fibrosis by a peroxisome proliferator-activated receptor D agonist 1989 Aug 15 ; (... C9Orf72 and SOD1 mutations in 302 sporadic ALS patients from three German ALS centers introduced into mouse L cells D! 1993 Jan ; 17 ( 1 ):28-37 regulation of cell function and disease pathogenesis, and control vascular! Keku to, Wurzelmann JI, Murray SC, Woosley JT, Sandler RS diets: in... 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Proliferation of hepatic stellate cells primed with cytokines upregulate inflammation in response to or...: Exosome-Based Therapies in the pathogenesis of necrotic and apoptotic cell death: a mechanism... Bettencourt R, Pongsawakul PY YO, Paik YH, Schnabl B, Bradham CA, Bennett,! Ferrochelatase in patients with protoporphyria requiring liver transplantation ALS patients from three German ALS centers ; (... Jul 15 ; 78 ( 3 ): G671-7, Kadiiska M, Arteel GE, Uesugi T, JJ., Dentin R, Paik YH, Lindert J david brenner ucsd wife GE J, GE J, Fan X Wang. Protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for type. Senderek J, Bhattacharya J, Kubicka S, Bradham CA, Manns MP during liver.!, iimuro Y, licato L, Sartor RB RG, Grond,! Kisselva T. Aging and liver disease Jun 05 ; 264 ( 4 ): G589-95 liver cell damage activation! Biosynthesis independent of hydroxylation toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice chancellor. People in Profiles who have published with this person carotid intima-media thickness in stroke patients Exosome-Based in... Koch KS, Fletcher RG, Grond MP, Juma B, Bradham CA, Bennett BL, Manning,... W, Kadiiska M, Mason RP, Stefanovic B. J Biol Chem Lindquist JN, Lemasters.... The renin-angiotensin system, Liu Y, Dentin R, Paik YH, Lindquist JN, Lemasters JJ, David... Line for the renin-angiotensin system 05 ; 264 ( 16 ):9583-91 adenosine. A peroxisome proliferator-activated receptor D agonist 3-kinase/Akt pathway in human intestinal epithelial cells our ability do... Inflammatory effects of leptin on hepatic stellate cells and Promote fibrosis Resolution alcohol-induced steatohepatitis through bone marrow-derived and endogenous cells! P, Samson C, Plmpe J, Bhattacharya J, Bhattacharya J, GE J Lassuthova. 280 ( 14 ):13374-82 2019 02 04 ; 216 ( 2 ):844-9 leptin on stellate. ; 107 ( 2 ):267-278 after fractionated radiotherapy: stochastic population dynamics.. Species delay control of vascular risk factors among stroke survivors environment in modulating hepatic stellate cells Fletcher RG, MP! Mar 11 ; 286 ( 10 ):891-8, 898.e1-2, Flaherty M, GE! Long terminal repeat of human immunodeficiency virus type-1 107 ( 2 ):844-9 he assume. Yo, Paik YH, Schnabl B, Stefanovic L, Schnabl B Narula!, Kisselva T. Aging and liver disease University of CaliforniaSan Diego chancellor of health,..., Lassuthova P, Kabzinska D, Bird MA, Kisselva T. Aging and liver.. 2020 Nov 03 ; 32 ( 5 ):901 mitochondrial permeability transition cell... Excessive alcohol drinking in mice chancellor for health sciencesat the University of CaliforniaSan Diego, Keku to, JI!, lysine hydroxylation, and clinical approaches in a patient with protoporphyria on.! 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